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Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen

Vaccines effective against intracellular pathogens could save the lives of millions of people every year, but vaccine development has been hampered by the slow largely empirical search for protective antigens. In vivo highly expressed antigens might represent a small attractive antigen subset that c...

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Hlavní autoři: Rollenhagen, Claudia, Sörensen, Meike, Rizos, Konstantin, Hurvitz, Robert, Bumann, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC423265/
https://ncbi.nlm.nih.gov/pubmed/15173591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401283101
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