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Directed antigen delivery as a vaccine strategy for an intracellular bacterial pathogen

We have developed a vaccine strategy for generating an attenuated strain of an intracellular bacterial pathogen that, after uptake by professional antigen-presenting cells, does not replicate intracellularly and is readily killed. However, after degradation of the vaccine strain within the phagolyso...

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Detalhes bibliográficos
Main Authors: Bouwer, H. G. Archie, Alberti-Segui, Christine, Montfort, Megan J., Berkowitz, Nathan D., Higgins, Darren E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458801/
https://ncbi.nlm.nih.gov/pubmed/16549792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509381103
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