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The Supraspliceosome — A Multi-Task Machine for Regulated Pre-mRNA Processing in the Cell Nucleus
Pre-mRNA splicing of Pol II transcripts is executed in the mammalian cell nucleus within a huge (21 MDa) and highly dynamic RNP machine — the supraspliceosome. It is composed of four splicing active native spliceosomes, each resembling an in vitro assembled spliceosome, which are connected by the pr...
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| Published in: | Comput Struct Biotechnol J |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Research Network of Computational and Structural Biotechnology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4232567/ https://ncbi.nlm.nih.gov/pubmed/25408845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.09.008 |
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