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Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome

MicroRNAs (miRNAs) are central regulators of gene expression, and a large fraction of them are encoded in introns of RNA polymerase II transcripts. Thus, the biogenesis of intronic miRNAs by the microprocessor and the splicing of their host introns by the spliceosome require coordination between the...

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Detalles Bibliográficos
Autores principales: Agranat-Tamir, Lily, Shomron, Noam, Sperling, Joseph, Sperling, Ruth
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985634/
https://ncbi.nlm.nih.gov/pubmed/24464992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1413
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