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Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome

MicroRNAs (miRNAs) are central regulators of gene expression, and a large fraction of them are encoded in introns of RNA polymerase II transcripts. Thus, the biogenesis of intronic miRNAs by the microprocessor and the splicing of their host introns by the spliceosome require coordination between the...

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Détails bibliographiques
Auteurs principaux: Agranat-Tamir, Lily, Shomron, Noam, Sperling, Joseph, Sperling, Ruth
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985634/
https://ncbi.nlm.nih.gov/pubmed/24464992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1413
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