Redox-Responsive, Core-Cross-Linked Micelles Capable of On-Demand, Concurrent Drug Release and Structure Disassembly

We developed camptothecin (CPT)-conjugated, core-cross-linked (CCL) micelles that are subject to redox-responsive cleavage of the built-in disulfide bonds, resulting in disruption of the micellar structure and rapid release of CPT. CCL micelles were prepared via co-precipitation of disulfide-contain...

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Bibliografiske detaljer
Udgivet i:Biomacromolecules
Main Authors: Wang, Hua, Tang, Li, Tu, Chunlai, Song, Ziyuan, Yin, Qian, Yin, Lichen, Zhang, Zhonghai, Cheng, Jianjun
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232441/
https://ncbi.nlm.nih.gov/pubmed/24003893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm401086d
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