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The 5′-HS4 chicken β-globin insulator is a CTCF-dependent nuclear matrix-associated element

The protein CTCF plays an essential role in the action of a widely distributed class of vertebrate enhancer-blocking insulators, of which the first example was found in a DNA sequence element, HS4, at the 5′ end of the chicken β-globin locus. HS4 contains a binding site for CTCF that is necessary an...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yusufzai, Timur M., Felsenfeld, Gary
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423244/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15169959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402938101
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