Development of Stable Vibrio cholerae O1 Hikojima Type Vaccine Strains Co–Expressing the Inaba and Ogawa Lipopolysaccharide Antigens

We describe here the development of stable classical and El Tor V. cholerae O1 strains of the Hikojima serotype that co–express the Inaba and Ogawa antigens of O1 lipopolysaccharide (LPS). Mutation of the wbeT gene reduced LPS perosamine methylation and thereby gave only partial transformation into...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Karlsson, Stefan L., Ax, Elisabeth, Nygren, Erik, Källgård, Susanne, Blomquist, Margareta, Ekman, Annelie, Benktander, John, Holmgren, Jan, Lebens, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232259/
https://ncbi.nlm.nih.gov/pubmed/25397871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108521
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