Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma

BACKGROUND: Recent conflicting reports have found both brain tumor hypercellularity and necrosis in regions of restricted diffusion on MRI-derived apparent diffusion coefficient (ADC) images. This study precisely compares ADC and cell density voxel by voxel using postmortem human whole brain samples...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: LaViolette, Peter S., Mickevicius, Nikolai J., Cochran, Elizabeth J., Rand, Scott D., Connelly, Jennifer, Bovi, Joseph A., Malkin, Mark G., Mueller, Wade M., Schmainda, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232087/
https://ncbi.nlm.nih.gov/pubmed/25059209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou142
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