Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma

BACKGROUND: Recent conflicting reports have found both brain tumor hypercellularity and necrosis in regions of restricted diffusion on MRI-derived apparent diffusion coefficient (ADC) images. This study precisely compares ADC and cell density voxel by voxel using postmortem human whole brain samples...

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Vydáno v:Neuro Oncol
Hlavní autoři: LaViolette, Peter S., Mickevicius, Nikolai J., Cochran, Elizabeth J., Rand, Scott D., Connelly, Jennifer, Bovi, Joseph A., Malkin, Mark G., Mueller, Wade M., Schmainda, Kathleen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232087/
https://ncbi.nlm.nih.gov/pubmed/25059209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou142
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