Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial

BACKGROUND: Molecular biomarkers including isocitrate dehydrogenase 1 or 2 (IDH1/2) mutation, 1p/19q codeletion, and O(6)-methylguanine-DNA-methyltransferase (MGMT) promoter methylation may improve prognostication and guide treatment decisions for patients with World Health Organization (WHO) anapla...

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Vydáno v:Neuro Oncol
Hlavní autoři: Wiestler, Benedikt, Capper, David, Hovestadt, Volker, Sill, Martin, Jones, David T.W., Hartmann, Christian, Felsberg, Joerg, Platten, Michael, Feiden, Wolfgang, Keyvani, Kathy, Pfister, Stefan M., Wiestler, Otmar D., Meyermann, Richard, Reifenberger, Guido, Pietsch, Thorsten, von Deimling, Andreas, Weller, Michael, Wick, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232086/
https://ncbi.nlm.nih.gov/pubmed/25028501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou138
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