Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial

BACKGROUND: Molecular biomarkers including isocitrate dehydrogenase 1 or 2 (IDH1/2) mutation, 1p/19q codeletion, and O(6)-methylguanine-DNA-methyltransferase (MGMT) promoter methylation may improve prognostication and guide treatment decisions for patients with World Health Organization (WHO) anapla...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wiestler, Benedikt, Capper, David, Hovestadt, Volker, Sill, Martin, Jones, David T.W., Hartmann, Christian, Felsberg, Joerg, Platten, Michael, Feiden, Wolfgang, Keyvani, Kathy, Pfister, Stefan M., Wiestler, Otmar D., Meyermann, Richard, Reifenberger, Guido, Pietsch, Thorsten, von Deimling, Andreas, Weller, Michael, Wick, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232086/
https://ncbi.nlm.nih.gov/pubmed/25028501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou138
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