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Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region(1)(2)(3)(4)(5)(6)

Background: Although a higher consumption of alcohol, which is a methyl-group antagonist, was previously associated with colorectal cancer risk, mechanisms remain poorly understood. Objective: We hypothesized that excess alcohol consumption might increase risk of colorectal carcinoma with hypomethyl...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Clin Nutr
Hauptverfasser: Nishihara, Reiko, Wang, Molin, Qian, Zhi Rong, Baba, Yoshifumi, Yamauchi, Mai, Mima, Kosuke, Sukawa, Yasutaka, Kim, Sun A, Inamura, Kentaro, Zhang, Xuehong, Wu, Kana, Giovannucci, Edward L, Chan, Andrew T, Fuchs, Charles S, Ogino, Shuji, Schernhammer, Eva S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Nutrition 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232016/
https://ncbi.nlm.nih.gov/pubmed/25411283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.114.095539
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