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Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region(1)(2)(3)(4)(5)(6)

Background: Although a higher consumption of alcohol, which is a methyl-group antagonist, was previously associated with colorectal cancer risk, mechanisms remain poorly understood. Objective: We hypothesized that excess alcohol consumption might increase risk of colorectal carcinoma with hypomethyl...

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Publicado en:Am J Clin Nutr
Autores principales: Nishihara, Reiko, Wang, Molin, Qian, Zhi Rong, Baba, Yoshifumi, Yamauchi, Mai, Mima, Kosuke, Sukawa, Yasutaka, Kim, Sun A, Inamura, Kentaro, Zhang, Xuehong, Wu, Kana, Giovannucci, Edward L, Chan, Andrew T, Fuchs, Charles S, Ogino, Shuji, Schernhammer, Eva S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Nutrition 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232016/
https://ncbi.nlm.nih.gov/pubmed/25411283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.114.095539
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