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Substitution of natural sensory input by artificial neurostimulation of an amputated trigeminal nerve does not prevent the degeneration of basal forebrain cholinergic circuits projecting to the somatosensory cortex

Peripheral deafferentation downregulates acetylcholine (ACh) synthesis in sensory cortices. However, the responsible neural circuits and processes are not known. We irreversibly transected the rat infraorbital nerve and implanted neuroprosthetic microdevices for proximal stump stimulation, and asses...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Herrera-Rincon, Celia, Panetsos, Fivos
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231972/
https://ncbi.nlm.nih.gov/pubmed/25452715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00385
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