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Substitution of natural sensory input by artificial neurostimulation of an amputated trigeminal nerve does not prevent the degeneration of basal forebrain cholinergic circuits projecting to the somatosensory cortex

Peripheral deafferentation downregulates acetylcholine (ACh) synthesis in sensory cortices. However, the responsible neural circuits and processes are not known. We irreversibly transected the rat infraorbital nerve and implanted neuroprosthetic microdevices for proximal stump stimulation, and asses...

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Библиографические подробности
Опубликовано в: :Front Cell Neurosci
Главные авторы: Herrera-Rincon, Celia, Panetsos, Fivos
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231972/
https://ncbi.nlm.nih.gov/pubmed/25452715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00385
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