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Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae

The spindle checkpoint arrests cells at the metaphase-to-anaphase transition until all chromosomes have properly attached to the mitotic spindle. Checkpoint proteins Mad2p and Mad3p/BubR1p bind and inhibit Cdc20p, an activator for the anaphase-promoting complex (APC). We find that upon spindle check...

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Bibliographic Details
Main Authors: Pan, Jing, Chen, Rey-Huei
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC423194/
https://ncbi.nlm.nih.gov/pubmed/15198982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1184204
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