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Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae
The spindle checkpoint arrests cells at the metaphase-to-anaphase transition until all chromosomes have properly attached to the mitotic spindle. Checkpoint proteins Mad2p and Mad3p/BubR1p bind and inhibit Cdc20p, an activator for the anaphase-promoting complex (APC). We find that upon spindle check...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC423194/ https://ncbi.nlm.nih.gov/pubmed/15198982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1184204 |
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