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Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential
The discovery of mammalian Toll-like receptors (TLRs), first identified in 1997 based on their homology with Drosophila Toll, greatly altered our understanding of how the innate immune system recognizes and responds to diverse microbial pathogens. TLRs are evolutionarily conserved type I transmembra...
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| Publicado no: | Clin Sci (Lond) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231819/ https://ncbi.nlm.nih.gov/pubmed/21745188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20110164 |
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