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Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

The discovery of mammalian Toll-like receptors (TLRs), first identified in 1997 based on their homology with Drosophila Toll, greatly altered our understanding of how the innate immune system recognizes and responds to diverse microbial pathogens. TLRs are evolutionarily conserved type I transmembra...

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Bibliografiske detaljer
Udgivet i:Clin Sci (Lond)
Main Authors: Hanke, Mark L., Kielian, Tammy
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231819/
https://ncbi.nlm.nih.gov/pubmed/21745188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20110164
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