A Direct Interaction between the Sigma-1 Receptor and the hERG Voltage-gated K(+) Channel Revealed by Atomic Force Microscopy and Homogeneous Time-resolved Fluorescence (HTRF®)

The sigma-1 receptor is an endoplasmic reticulum chaperone protein, widely expressed in central and peripheral tissues, which can translocate to the plasma membrane and modulate the function of various ion channels. The human ether-à-go-go-related gene encodes hERG, a cardiac voltage-gated K(+) chan...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Balasuriya, Dilshan, D'Sa, Lauren, Talker, Ronel, Dupuis, Elodie, Maurin, Fabrice, Martin, Patrick, Borgese, Franck, Soriani, Olivier, Edwardson, J. Michael
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231707/
https://ncbi.nlm.nih.gov/pubmed/25266722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603506
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