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Global Ablation of the Mouse Rab11a Gene Impairs Early Embryogenesis and Matrix Metalloproteinase Secretion

Rab11a has been conceived as a prominent regulatory component of the recycling endosome, which acts as a nexus in the endo- and exocytotic networks. The precise in vivo role of Rab11a in mouse embryonic development is unknown. We globally ablated Rab11a and examined the phenotypic and molecular outc...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Yu, Shiyan, Yehia, Ghassan, Wang, Juanfei, Stypulkowski, Ewa, Sakamori, Ryotaro, Jiang, Ping, Hernandez-Enriquez, Berenice, Tran, Tracy S., Bonder, Edward M., Guo, Wei, Gao, Nan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231680/
https://ncbi.nlm.nih.gov/pubmed/25271168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.538223
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