Mutational Analysis of Cysteine Residues of the Insect Odorant Co-receptor (Orco) from Drosophila melanogaster Reveals Differential Effects on Agonist- and Odorant-tuning Receptor-dependent Activation

Insect odorant receptors are heteromeric odorant-gated cation channels comprising a conventional odorant-sensitive tuning receptor (ORx) and a highly conserved co-receptor known as Orco. Orco is found only in insects, and very little is known about its structure and the mechanism leading to channel...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Turner, Rebecca M., Derryberry, Stephen L., Kumar, Brijesh N., Brittain, Thomas, Zwiebel, Laurence J., Newcomb, Richard D., Christie, David L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231661/
https://ncbi.nlm.nih.gov/pubmed/25271160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603993
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