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Narrow SAR in odorant sensing Orco receptor agonists

The systematic exploration of a series of triazole-based agonists of the cation channel insect odorant receptor is reported. The structure-activity relationships of independent sections of the molecules are examined. Very small changes to the compound structure were found to exert a large impact on...

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Detalhes bibliográficos
Main Authors: Romaine, Ian M., Taylor, Robert W., Saidu, Samsudeen P., Kim, Kwangho, Sulikowski, Gary A., Zwiebel, Laurence J., Waterson, Alex G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111141/
https://ncbi.nlm.nih.gov/pubmed/24813736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.04.081
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