New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases

The function of neutrophil protease 3 (PR3) is poorly understood despite of its role in autoimmune vasculitides and its possible involvement in cell apoptosis. This makes it different from its structural homologue neutrophil elastase (HNE). Endogenous inhibitors of human neutrophil serine proteases...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Guarino, Carla, Legowska, Monika, Epinette, Christophe, Kellenberger, Christine, Dallet-Choisy, Sandrine, Sieńczyk, Marcin, Gabant, Guillaume, Cadene, Martine, Zoidakis, Jérôme, Vlahou, Antonia, Wysocka, Magdalena, Marchand-Adam, Sylvain, Jenne, Dieter E., Lesner, Adam, Gauthier, Francis, Korkmaz, Brice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231656/
https://ncbi.nlm.nih.gov/pubmed/25288799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591339
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