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Integration and Oligomerization of Bax Protein in Lipid Bilayers Characterized by Single Molecule Fluorescence Study

Bax is a pro-apoptotic Bcl-2 family protein. The activated Bax translocates to mitochondria, where it forms pore and permeabilizes the mitochondrial outer membrane. This process requires the BH3-only activator protein (i.e. tBid) and can be inhibited by anti-apoptotic Bcl-2 family proteins such as B...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Luo, Lu, Yang, Jun, Liu, Dongxiang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231651/
https://ncbi.nlm.nih.gov/pubmed/25288797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.583393
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