Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism

The molecular mechanism of autophagy and its relationship to other lysosomal degradation pathways remain incompletely understood. Here, we identified a previously uncharacterized mammalian-specific protein, Beclin 2, which like Beclin 1, functions in autophagy and interacts with class III PI3K compl...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: He, Congcong, Wei, Yongjie, Sun, Kai, Li, Binghua, Dong, Xiaonan, Zou, Zhongju, Liu, Yang, Kinch, Lisa N., Khan, Shaheen, Sinha, Sangita, Xavier, Ramnik J., Grishin, Nick V., Xiao, Guanghua, Eskelinen, Eeva-Liisa, Scherer, Philipp E., Whistler, Jennifer L., Levine, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231430/
https://ncbi.nlm.nih.gov/pubmed/23954414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.035
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