Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels

Plasminogen is the precursor of the serine protease plasmin, a central enzyme of the fibrinolytic system. Plasma levels of plasminogen vary by almost 2-fold among healthy individuals, yet little is known about its heritability or genetic determinants in the general population. In order to identify g...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Ma, Qianyi, Ozel, Ayse B., Ramdas, Shweta, McGee, Beth, Khoriaty, Rami, Siemieniak, David, Li, Hong-Dong, Guan, Yuanfang, Brody, Lawrence C., Mills, James L., Molloy, Anne M., Ginsburg, David, Li, Jun Z., Desch, Karl C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2014
Onderwerpen:
Thrombosis and Hemostasis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231423/
https://ncbi.nlm.nih.gov/pubmed/25208887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-560086
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