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CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis

Knockout of genes with CRISPR/Cas9 is a newly emerged approach to investigate functions of genes in various organisms. We demonstrate that CRISPR/Cas9 can mutate endogenous genes of the ascidian Ciona intestinalis, a splendid model for elucidating molecular mechanisms for constructing the chordate b...

詳細記述

保存先:
書誌詳細
出版年:Dev Growth Differ
主要な著者: Sasaki, Haruka, Yoshida, Keita, Hozumi, Akiko, Sasakura, Yasunori
フォーマット: Artigo
言語:Inglês
出版事項: BlackWell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231237/
https://ncbi.nlm.nih.gov/pubmed/25212715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dgd.12149
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