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CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis
Knockout of genes with CRISPR/Cas9 is a newly emerged approach to investigate functions of genes in various organisms. We demonstrate that CRISPR/Cas9 can mutate endogenous genes of the ascidian Ciona intestinalis, a splendid model for elucidating molecular mechanisms for constructing the chordate b...
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| Publicado no: | Dev Growth Differ |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231237/ https://ncbi.nlm.nih.gov/pubmed/25212715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dgd.12149 |
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