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Subcutaneous pulsatile glucocorticoid replacement therapy

The glucocorticoid hormone cortisol is released in pulses resulting in a complex and dynamic ultradian rhythm of plasma cortisol that underlies the classical circadian rhythm. These oscillating levels are also seen at the level of tissues such as the brain and trigger pulses of gene activation and d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Endocrinol (Oxf)
Hauptverfasser: Russell, Georgina M, Durant, Claire, Ataya, Alia, Papastathi, Chrysoula, Bhake, Ragini, Woltersdorf, Wolfram, Lightman, Stafford
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231230/
https://ncbi.nlm.nih.gov/pubmed/24735400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cen.12470
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