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Mitochondria selective S-nitrosation by mitochondria-targeted S-nitrosothiol protects against post-infarct heart failure in mouse hearts

AIMS: Recently it has been shown that the mitochondria-targeted S-nitrosothiol MitoSNO protects against acute ischaemia/reperfusion (IR) injury by inhibiting the reactivation of mitochondrial complex I in the first minutes of reperfusion of ischaemic tissue, thereby preventing free radical formation...

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Detalles Bibliográficos
Publicado en:Eur J Heart Fail
Autores principales: Methner, Carmen, Chouchani, Edward T, Buonincontri, Guido, Pell, Victoria R, Sawiak, Stephen J, Murphy, Michael P, Krieg, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231226/
https://ncbi.nlm.nih.gov/pubmed/24891297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.100
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