Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions

The initial interaction between HIV-1 and the host occurs at the mucosa during sexual intercourse. In cervical mucosa, HIV-1 exists both as free and opsonized virions and this might influence initial infection. We used cervical explants to study HIV-1 transmission, the effects of opsonization on inf...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Tjomsland, Veronica, Ellegård, Rada, Kjölhede, Preben, Wodlin, Ninni Borendal, Hinkula, Jorma, Lifson, Jeffrey D, Larsson, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Immunity to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231223/
https://ncbi.nlm.nih.gov/pubmed/23686382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243257
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