Complement Opsonization of HIV-1 Results in Decreased Antiviral and Inflammatory Responses in Immature Dendritic Cells via CR3

Immature dendritic cells (iDCs) in genital and rectal mucosa may be one of the first cells to come into contact with HIV-1 during sexual transmission of virus. HIV-1 activates the host complement system, which results in opsonization of virus by inactivated complement fragments, for example, iC3b. W...

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Hlavní autoři: Ellegård, Rada, Crisci, Elisa, Burgener, Adam, Sjöwall, Christopher, Birse, Kenzie, Westmacott, Garrett, Hinkula, Jorma, Lifson, Jeffrey D., Larsson, Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2014
Témata:
Innate Immunity and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201991/
https://ncbi.nlm.nih.gov/pubmed/25252956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401781
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