Complement Opsonization of HIV-1 Results in Decreased Antiviral and Inflammatory Responses in Immature Dendritic Cells via CR3

Immature dendritic cells (iDCs) in genital and rectal mucosa may be one of the first cells to come into contact with HIV-1 during sexual transmission of virus. HIV-1 activates the host complement system, which results in opsonization of virus by inactivated complement fragments, for example, iC3b. W...

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Detalhes bibliográficos
Main Authors: Ellegård, Rada, Crisci, Elisa, Burgener, Adam, Sjöwall, Christopher, Birse, Kenzie, Westmacott, Garrett, Hinkula, Jorma, Lifson, Jeffrey D., Larsson, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2014
Assuntos:
Innate Immunity and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201991/
https://ncbi.nlm.nih.gov/pubmed/25252956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401781
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