Human Adipose-Derived Mesenchymal Stem Cells as a New Model of Spinal and Bulbar Muscular Atrophy

Spinal and bulbar muscular atrophy (SBMA) or Kennedy's disease is an X-linked CAG/polyglutamine expansion motoneuron disease, in which an elongated polyglutamine tract (polyQ) in the N-terminal androgen receptor (ARpolyQ) confers toxicity to this protein. Typical markers of SBMA disease are ARp...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Dossena, Marta, Bedini, Gloria, Rusmini, Paola, Giorgetti, Elisa, Canazza, Alessandra, Tosetti, Valentina, Salsano, Ettore, Sagnelli, Anna, Mariotti, Caterina, Gellera, Cinzia, Navone, Stefania Elena, Marfia, Giovanni, Alessandri, Giulio, Corsi, Fabio, Parati, Eugenio Agostino, Pareyson, Davide, Poletti, Angelo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231043/
https://ncbi.nlm.nih.gov/pubmed/25392924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112746
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