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A novel high-throughput in vitro model for identifying hemodynamic-induced inflammatory mediators of cerebral aneurysm formation

Cerebral aneurysms are thought to develop at locations of hemodynamic shear stress, via an inflammatory process. The molecular mechanism that links shear stress to inflammation, however, is not completely understood. Progress in studying this disease is limited by a lack of a suitable in vitro model...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Nowicki, Kamil W., Hosaka, Koji, He, Yong, McFetridge, Peter S., Scott, Edward W., Hoh, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231007/
https://ncbi.nlm.nih.gov/pubmed/25225207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03775
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