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A novel high-throughput in vitro model for identifying hemodynamic-induced inflammatory mediators of cerebral aneurysm formation

Cerebral aneurysms are thought to develop at locations of hemodynamic shear stress, via an inflammatory process. The molecular mechanism that links shear stress to inflammation, however, is not completely understood. Progress in studying this disease is limited by a lack of a suitable in vitro model...

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Bibliografiske detaljer
Udgivet i:Hypertension
Main Authors: Nowicki, Kamil W., Hosaka, Koji, He, Yong, McFetridge, Peter S., Scott, Edward W., Hoh, Brian L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231007/
https://ncbi.nlm.nih.gov/pubmed/25225207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03775
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