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Transition State Analysis of Enantioselective Brønsted Base Catalysis by Chiral Cyclopropenimines

[Image: see text] Experimental (13)C kinetic isotope effects have been used to interrogate the rate-limiting step of the Michael addition of glycinate imines to benzyl acrylate catalyzed by a chiral 2,3-bis(dicyclohexylamino) cyclopropenimine catalyst. The reaction is found to proceed via rate-limit...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Bandar, Jeffrey S., Sauer, Gregory S., Wulff, William D., Lambert, Tristan H., Vetticatt, Mathew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230825/
https://ncbi.nlm.nih.gov/pubmed/25029194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja504532d
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