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Latency of transcription factor Stp1 depends on a modular regulatory motif that functions as cytoplasmic retention determinant and nuclear degron
The Ssy1-Ptr3-Ssy5 (SPS)–sensing pathway enables yeast to respond to extracellular amino acids. Stp1, the effector transcription factor, is synthesized as a latent cytoplasmic precursor with an N-terminal regulatory domain that restricts its nuclear accumulation. The negative regulatory mechanisms i...
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| Publicado no: | Mol Biol Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4230787/ https://ncbi.nlm.nih.gov/pubmed/25253722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1140 |
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