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Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death

Recently the ESCRT-III filamentous complex was designated as the driving force for mammalian cell abscission, that is, fission of the intercellular membrane bridge connecting daughter cells at the end of cytokinesis. However, how ESCRT-III is activated to set on abscission has not been resolved. Her...

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Pubblicato in:Mol Biol Cell
Autori principali: Goliand, Inna, Nachmias, Dikla, Gershony, Ofir, Elia, Natalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230781/
https://ncbi.nlm.nih.gov/pubmed/25232011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1317
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