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Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death

Recently the ESCRT-III filamentous complex was designated as the driving force for mammalian cell abscission, that is, fission of the intercellular membrane bridge connecting daughter cells at the end of cytokinesis. However, how ESCRT-III is activated to set on abscission has not been resolved. Her...

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Publicat a:Mol Biol Cell
Autors principals: Goliand, Inna, Nachmias, Dikla, Gershony, Ofir, Elia, Natalie
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230781/
https://ncbi.nlm.nih.gov/pubmed/25232011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1317
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