Comparative efficacy of a multi-epitope DNA vaccine via intranasal, peroral, and intramuscular delivery against lethal Toxoplasma gondii infection in mice

BACKGROUND: Toxoplasmosis is an important zoonosis, being a cause of congenital disease and abortion in animals and humans. DNA vaccination as a promising vaccine remains a challenge for an improved delivery system. METHODS: In this study, attenuated Salmonella typhimurium BRD509 was used to deliver...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Cong, Hua, Yuan, Quan, Zhao, Qunli, Zhao, Lingxiao, Yin, Huiquan, Zhou, Huaiyu, He, Shenyi, Wang, Zhiyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229990/
https://ncbi.nlm.nih.gov/pubmed/24685150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-7-145
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