Compound DNA vaccine encoding SAG1/ SAG3 with A(2)/B subunit of cholera toxin as a genetic adjuvant protects BALB/c mice against Toxoplasma gondii

BACKGROUND: Intracellular parasites, such as T. gondii, present a plurality of antigens because of the complexity of its life cycle. Compound DNA vaccines bring a new approach and hope for the treatment of toxoplasmosis. In this study, a DNA vaccine encoding two major surface antigens SAG1, SAG3 fro...

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Bibliografiske detaljer
Main Authors: Cong, Hua, Zhang, Min, Xin, Qing, Wang, Zhiyu, Li, Ying, Zhao, Qunli, Zhou, Huaiyu, He, Shenyi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622580/
https://ncbi.nlm.nih.gov/pubmed/23497561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-6-63
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