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A statistical approach for inferring the 3D structure of the genome

Motivation: Recent technological advances allow the measurement, in a single Hi-C experiment, of the frequencies of physical contacts among pairs of genomic loci at a genome-wide scale. The next challenge is to infer, from the resulting DNA–DNA contact maps, accurate 3D models of how chromosomes fol...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Varoquaux, Nelle, Ay, Ferhat, Noble, William Stafford, Vert, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229903/
https://ncbi.nlm.nih.gov/pubmed/24931992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu268
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