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A statistical approach for inferring the 3D structure of the genome
Motivation: Recent technological advances allow the measurement, in a single Hi-C experiment, of the frequencies of physical contacts among pairs of genomic loci at a genome-wide scale. The next challenge is to infer, from the resulting DNA–DNA contact maps, accurate 3D models of how chromosomes fol...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229903/ https://ncbi.nlm.nih.gov/pubmed/24931992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu268 |
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