Overcoming multiple drug resistance mechanisms in medulloblastoma

INTRODUCTION: Medulloblastoma (MB) is the most common malignant paediatric brain tumour. Recurrence and progression of disease occurs in 15-20% of standard risk and 30-40% of high risk patients. We analysed whether circumvention of chemoresistance pathways (drug export, DNA repair and apoptotic inhi...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Othman, Ramadhan T, Kimishi, Ioanna, Bradshaw, Tracey D, Storer, Lisa CD, Korshunov, Andrey, Pfister, Stefan M, Grundy, Richard G, Kerr, Ian D, Coyle, Beth
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229867/
https://ncbi.nlm.nih.gov/pubmed/24887326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-57
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