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HIV-1 protease-induced apoptosis

BACKGROUND: Apoptosis is one of the presumptive causes of CD4(+) T cell depletion during HIV infection and progression to AIDS. However, the precise role of HIV-1 in this process remains unexplained. HIV-1 protease (PR) has been suggested as a possible factor, but a direct link between HIV-1 PR enzy...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Rumlová, Michaela, Křížová, Ivana, Keprová, Alena, Hadravová, Romana, Doležal, Michal, Strohalmová, Karolína, Pichová, Iva, Hájek, Miroslav, Ruml, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229777/
https://ncbi.nlm.nih.gov/pubmed/24886575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-37
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