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The effect of point mutations within the N-terminal domain of Mason-Pfizer monkey virus capsid protein on virus core assembly and infectivity

Retroviral capsid protein (CA) mediates protein interactions driving the assembly of both immature viral particles and the core of the mature virions. Structurally conserved N-terminal domains of several retroviruses refold after proteolytic cleavage into a β-hairpin, stabilized by a salt bridge bet...

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Bibliographic Details
Main Authors: Wildová, Marcela, Hadravová, Romana, Štokrová, Jitka, Křížová, Ivana, Ruml, Tomáš, Hunter, Eric, Pichová, Iva, Rumlová, Michaela
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779695/
https://ncbi.nlm.nih.gov/pubmed/18755489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.07.021
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