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Plasma lopinavir concentrations predict virological failure in a cohort of South African children initiating a protease-inhibitor-based regimen

BACKGROUND: Poor adherence to antiretroviral therapy contributes to pharmacokinetic variability and is the major determinant of virological failure. However, measuring treatment adherence is difficult, especially in children. We investigated the relationship between plasma lopinavir concentrations,...

詳細記述

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書誌詳細
出版年:Antivir Ther
主要な著者: Moholisa, Retsilisitsoe R, Schomaker, Michael, Kuhn, Louise, Meredith, Sandra, Wiesner, Lubbe, Coovadia, Ashraf, Strehlau, Renate, Martens, Leigh, Abrams, Elaine J, Maartens, Gary, Mcllleron, Helen
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229495/
https://ncbi.nlm.nih.gov/pubmed/24518130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2749
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