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Plasma lopinavir concentrations predict virological failure in a cohort of South African children initiating a protease-inhibitor-based regimen

BACKGROUND: Poor adherence to antiretroviral therapy contributes to pharmacokinetic variability and is the major determinant of virological failure. However, measuring treatment adherence is difficult, especially in children. We investigated the relationship between plasma lopinavir concentrations,...

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Detalhes bibliográficos
Publicado no:Antivir Ther
Main Authors: Moholisa, Retsilisitsoe R, Schomaker, Michael, Kuhn, Louise, Meredith, Sandra, Wiesner, Lubbe, Coovadia, Ashraf, Strehlau, Renate, Martens, Leigh, Abrams, Elaine J, Maartens, Gary, Mcllleron, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229495/
https://ncbi.nlm.nih.gov/pubmed/24518130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2749
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