IL28B Polymorphism Cannot Predict Response to Interferon Alpha Treatment in Patients with Melanoma

BACKGROUND: Recent genome-wide association studies revealed the rs12979860 single nucleotide polymorphism (SNP) of the IL28B gene (CC genotype) to be the strongest pre-therapeutic predictor of therapy response to interferon alpha in patients with chronic hepatitis C infection. The favorable CC genot...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Probst, Martin, Hoeller, Christoph, Ferenci, Peter, Staettermayer, Albert F., Beinhardt, Sandra, Pehamberger, Hubert, Kittler, Harald, Grabmeier-Pfistershammer, Katharina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229256/
https://ncbi.nlm.nih.gov/pubmed/25389973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112613
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