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Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells

The Sleeping Beauty (SB) transposon is a non-viral integrating vector system with proven efficacy for gene transfer and functional genomics. However, integration efficiency is negatively affected by the length of the transposon. To optimize the SB transposon machinery, the inverted repeats and the t...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Turchiano, Giandomenico, Latella, Maria Carmela, Gogol-Döring, Andreas, Cattoglio, Claudia, Mavilio, Fulvio, Izsvák, Zsuzsanna, Ivics, Zoltán, Recchia, Alessandra
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229213/
https://ncbi.nlm.nih.gov/pubmed/25390293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112712
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